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BMJ Open Diab Res Care
Acknowledgements This work was supported by the Shanghai Municipal Health Commission key priority discipline project, Shanghai Spinal Disease and Trauma Orthopedics Research Center (2022ZZ01014), and Shanghai Frontiers Science Center of Degeneration and Regeneration in Skeletal System (BJ1-9000-22-4002)
It binds to GLP-1 receptors found on: Pancreatic -cells Stimulates glucose-dependent insulin secretion Pancreatic -cells Suppresses glucagon release during hyperglycemia Hypothalamic satiety centers Reduces appetite and food intake Gastrointestinal tract Delays gastric emptying, enhancing satiety This multi-site activity leads to improved glycemic control, reduced body weight, and cardiovascular benefits
Du YT, Rayner CK, Jones KL, Talley NJ, Horowitz M (2018) Gastrointestinal symptoms in diabetes: prevalence, assessment, pathogenesis, and management
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